Short-term organoid culture for drug sensitivity testing of high-grade serous carcinoma

OBJECTIVE. Cancer patient-derived organoids (PDOs) grow as three dimensional (3D) structures in the presence of extracellular matrix and have been found to represent the original tumor’s genetic complexity. In addition, PDOs can be grown and subjected to drug sensitivity testing in a shorter time co...

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Bibliografische gegevens
Gepubliceerd in:Gynecol Oncol
Hoofdauteurs: Chen, Hui, Gotimer, Kristin, De Souza, Cristabelle, Tepper, Clifford G., Karnezis, Anthony N., Leiserowitz, Gary S., Chien, Jeremy, Smith, Lloyd H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7819712/
https://ncbi.nlm.nih.gov/pubmed/32253045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2020.03.026
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