Microtubule Engagement with Taxane Is Altered in Taxane-Resistant Gastric Cancer

PURPOSE: Although taxane-based therapy is standard treatment for advanced gastric cancer, a majority of patients exhibit intrinsic resistance to taxanes. Here, we aim to identify the molecular basis of taxane resistance in gastric cancer. EXPERIMENTAL DESIGN: We performed a post hoc analysis of the...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Galletti, Giuseppe, Zhang, Chao, Gjyrezi, Ada, Cleveland, Kyle, Zhang, Jiaren, Powell, Sarah, Thakkar, Prashant V., Betel, Doron, Shah, Manish A., Giannakakou, Paraskevi
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816968/
https://ncbi.nlm.nih.gov/pubmed/32321717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-3018
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