Identification of low abundance microbiome in clinical samples using whole genome sequencing

Identifying the microbiome composition from primary tissues directly affords an opportunity to study the causative relationships between the host microbiome and disease. However, this is challenging due the low abundance of microbial DNA relative to the host. We present a systematic evaluation of mi...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Zhang, Chao, Cleveland, Kyle, Schnoll-Sussman, Felice, McClure, Bridget, Bigg, Michelle, Thakkar, Prashant, Schultz, Nikolaus, Shah, Manish A., Betel, Doron
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
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Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661937/
https://ncbi.nlm.nih.gov/pubmed/26614063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0821-z
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