Identification of low abundance microbiome in clinical samples using whole genome sequencing

Identifying the microbiome composition from primary tissues directly affords an opportunity to study the causative relationships between the host microbiome and disease. However, this is challenging due the low abundance of microbial DNA relative to the host. We present a systematic evaluation of mi...

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Vydáno v:Genome Biol
Hlavní autoři: Zhang, Chao, Cleveland, Kyle, Schnoll-Sussman, Felice, McClure, Bridget, Bigg, Michelle, Thakkar, Prashant, Schultz, Nikolaus, Shah, Manish A., Betel, Doron
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Method
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661937/
https://ncbi.nlm.nih.gov/pubmed/26614063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0821-z
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