Identification of low abundance microbiome in clinical samples using whole genome sequencing

Identifying the microbiome composition from primary tissues directly affords an opportunity to study the causative relationships between the host microbiome and disease. However, this is challenging due the low abundance of microbial DNA relative to the host. We present a systematic evaluation of mi...

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Publicado en:Genome Biol
Autores principales: Zhang, Chao, Cleveland, Kyle, Schnoll-Sussman, Felice, McClure, Bridget, Bigg, Michelle, Thakkar, Prashant, Schultz, Nikolaus, Shah, Manish A., Betel, Doron
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Method
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661937/
https://ncbi.nlm.nih.gov/pubmed/26614063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0821-z
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