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Taxane resistance in prostate cancer is mediated by decreased drug-target engagement
Despite widespread use of taxanes, mechanisms of action and resistance in vivo remain to be established, and there is no way of predicting who will respond to therapy. This study examined prostate cancer (PCa) xenografts and patient samples to identify in vivo mechanisms of taxane action and resista...
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| Publicat a: | J Clin Invest |
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| Autors principals: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7259995/ https://ncbi.nlm.nih.gov/pubmed/32478682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI132184 |
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