Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

Dietary sugars, fructose and glucose, promote hepatic de novo lipogenesis and modify the effects of a high-fat diet (HFD) on the development of insulin resistance. Here, we show that fructose and glucose supplementation of an HFD exert divergent effects on hepatic mitochondrial function and fatty ac...

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Bibliographic Details
Published in:Cell Metab
Main Authors: Softic, Samir, Meyer, Jesse G., Wang, Guo-Xiao, Gupta, Manoj K., Batista, Thiago M., Lauritzen, Hans P.M.M., Fujisaka, Shiho, Serra, Dolors, Herrero, Laura, Willoughby, Jennifer, Fitzgerald, Kevin, Ilkayeva, Olga, Newgard, Christopher B., Gibson, Bradford W., Schilling, Birgit, Cohen, David E., Kahn, C. Ronald
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816129/
https://ncbi.nlm.nih.gov/pubmed/31577934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.09.003
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