The brown fat secretome: metabolic functions beyond thermogenesis

Por Wang, Guo-Xiao, Zhao, Xu-Yun, Lin, Jiandie D.
Publicado no Trends Endocrinol Metab (2015)

The Biological Clock is Regulated by Adrenergic Signaling in Brown Fat but is Dispensable for Cold-Induced Thermogenesis

Por Li, Siming, Yu, Qi, Wang, Guo-Xiao, Lin, Jiandie D.
Publicado em 2013

A Long Noncoding RNA Transcriptional Regulatory Circuit Drives Thermogenic Adipocyte Differentiation

Por Zhao, Xu-Yun, Li, Siming, Wang, Guo-Xiao, Yu, Qi, Lin, Jiandie D.
Publicado em 2014

Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis

Por Li, Siming, Mi, Lin, Yu, Lei, Yu, Qi, Liu, Tongyu, Wang, Guo-Xiao, Zhao, Xu-Yun, Wu, Jun, Lin, Jiandie D.
Publicado no Proc Natl Acad Sci U S A (2017)

Otopetrin 1 Protects Mice From Obesity-Associated Metabolic Dysfunction Through Attenuating Adipose Tissue Inflammation

Por Wang, Guo-Xiao, Cho, Kae Won, Uhm, Maeran, Hu, Chun-Rui, Li, Siming, Cozacov, Zoharit, Xu, Acer E., Cheng, Ji-Xin, Saltiel, Alan R., Lumeng, Carey N., Lin, Jiandie D.
Publicado em 2014

The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuating hepatic lipogenesis

Por Wang, Guo-Xiao, Zhao, Xu-Yun, Meng, Zhuo-Xian, Kern, Matthias, Dietrich, Arne, Chen, Zhimin, Cozacov, Zoharit, Zhou, Dequan, Okunade, Adewole L., Su, Xiong, Li, Siming, Blüher, Matthias, Lin, Jiandie D.
Publicado no Nat Med (2014)

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

Por Softic, Samir, Gupta, Manoj K., Wang, Guo-Xiao, Fujisaka, Shiho, O’Neill, Brian T., Rao, Tata Nageswara, Willoughby, Jennifer, Harbison, Carole, Fitzgerald, Kevin, Ilkayeva, Olga, Newgard, Christopher B., Cohen, David E., Kahn, C. Ronald
Publicado no J Clin Invest (2017)

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

Por Softic, Samir, Gupta, Manoj K., Wang, Guo-Xiao, Fujisaka, Shiho, O’Neill, Brian T., Rao, Tata Nageswara, Willoughby, Jennifer, Harbison, Carole, Fitzgerald, Kevin, Ilkayeva, Olga, Newgard, Christopher B., Cohen, David E., Kahn, C. Ronald
Publicado no J Clin Invest (2018)

Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders

Por Chen, Zhimin, Wang, Guo-Xiao, Ma, Sara L., Jung, Dae Young, Ha, Hyekyung, Altamimi, Tariq, Zhao, Xu-Yun, Guo, Liang, Zhang, Peng, Hu, Chun-Rui, Cheng, Ji-Xin, Lopaschuk, Gary D., Kim, Jason K., Lin, Jiandie D.
Publicado no Mol Metab (2017)

Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

Por Softic, Samir, Meyer, Jesse G., Wang, Guo-Xiao, Gupta, Manoj K., Batista, Thiago M., Lauritzen, Hans P.M.M., Fujisaka, Shiho, Serra, Dolors, Herrero, Laura, Willoughby, Jennifer, Fitzgerald, Kevin, Ilkayeva, Olga, Newgard, Christopher B., Gibson, Bradford W., Schilling, Birgit, Cohen, David E., Kahn, C. Ronald
Publicado no Cell Metab (2019)