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The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuating hepatic lipogenesis

Brown fat activates uncoupled respiration to defend against cold and contributes to systemic metabolic homeostasis. To date, the metabolic action of brown fat has been primarily attributed to its role in fuel oxidation and uncoupling protein 1 (UCP1)-mediated thermogenesis. Whether brown fat engages...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Wang, Guo-Xiao, Zhao, Xu-Yun, Meng, Zhuo-Xian, Kern, Matthias, Dietrich, Arne, Chen, Zhimin, Cozacov, Zoharit, Zhou, Dequan, Okunade, Adewole L., Su, Xiong, Li, Siming, Blüher, Matthias, Lin, Jiandie D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257907/
https://ncbi.nlm.nih.gov/pubmed/25401691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3713
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