Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

Dietary sugars, fructose and glucose, promote hepatic de novo lipogenesis and modify the effects of a high-fat diet (HFD) on the development of insulin resistance. Here, we show that fructose and glucose supplementation of an HFD exert divergent effects on hepatic mitochondrial function and fatty ac...

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Publicat a:Cell Metab
Autors principals: Softic, Samir, Meyer, Jesse G., Wang, Guo-Xiao, Gupta, Manoj K., Batista, Thiago M., Lauritzen, Hans P.M.M., Fujisaka, Shiho, Serra, Dolors, Herrero, Laura, Willoughby, Jennifer, Fitzgerald, Kevin, Ilkayeva, Olga, Newgard, Christopher B., Gibson, Bradford W., Schilling, Birgit, Cohen, David E., Kahn, C. Ronald
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816129/
https://ncbi.nlm.nih.gov/pubmed/31577934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.09.003
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