Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation

Brown adipose tissue (BAT) is rich in mitochondria and plays important roles in energy expenditure, thermogenesis and glucose homeostasis. We find that levels of mitochondrial protein succinylation and malonylation are high in BAT and subject to physiological and genetic regulation. BAT-specific del...

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Publicado en:Mol Cell
Autores principales: Wang, Guoxiao, Meyer, Jesse G., Cai, Weikang, Softic, Samir, Li, Mengyao Ella, Verdin, Eric, Newgard, Christopher, Schilling, Birgit, Kahn, C. Ronald
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525068/
https://ncbi.nlm.nih.gov/pubmed/31000437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.03.021
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