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Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles
The ATP-binding cassette transporter ABCG2 mediates the efflux of several chemotherapeutic drugs, contributing to the development of multidrug resistance (MDR) in many cancers. The most promising strategy to overcome ABCG2-mediated MDR is the use of specific inhibitors. Despite many efforts, the ide...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7815716/ https://ncbi.nlm.nih.gov/pubmed/33469044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79892-w |
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