Phenolic indeno[1,2-b]indoles as ABCG2-selective potent and non-toxic inhibitors stimulating basal ATPase activity

Ketonic indeno[1,2-b]indole-9,10-dione derivatives, initially designed as human casein kinase II (CK2) inhibitors, were recently shown to be converted into efficient inhibitors of drug efflux by the breast cancer resistance protein ABCG2 upon suited substitutions including a N(5)-phenethyl on C-ring...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Drug Des Devel Ther
Hlavní autoři: Gozzi, Gustavo Jabor, Bouaziz, Zouhair, Winter, Evelyn, Daflon-Yunes, Nathalia, Honorat, Mylène, Guragossian, Nathalie, Marminon, Christelle, Valdameri, Glaucio, Bollacke, Andre, Guillon, Jean, Pinaud, Noël, Marchivie, Mathieu, Cadena, Silvia M, Jose, Joachim, Le Borgne, Marc, Di Pietro, Attilio
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498724/
https://ncbi.nlm.nih.gov/pubmed/26170632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S84982
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky