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Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Substituted Indeno[1,2-b]indole Derivative, Discovered as CK2 Inhibitor

Protein kinase CK2 is involved in regulating cellular processes, such as cell cycle, proliferation, migration, and apoptosis, making it an attractive anticancer target. We previously described a prenyloxy-substituted indeno[1,2-b]indole (5-isopropyl-4-(3-methylbut-2-enyloxy)-5,6,7,8-tetrahydroindeno...

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Bibliografske podrobnosti
izdano v:Pharmaceuticals (Basel)
Main Authors: El-Awaad, Ehab, Birus, Robin, Marminon, Christelle, Bouaziz, Zouhair, Ballentin, Laurens, Aichele, Dagmar, Le Borgne, Marc, Jose, Joachim
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226678/
https://ncbi.nlm.nih.gov/pubmed/34198928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14060542
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