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Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Substituted Indeno[1,2-b]indole Derivative, Discovered as CK2 Inhibitor

Protein kinase CK2 is involved in regulating cellular processes, such as cell cycle, proliferation, migration, and apoptosis, making it an attractive anticancer target. We previously described a prenyloxy-substituted indeno[1,2-b]indole (5-isopropyl-4-(3-methylbut-2-enyloxy)-5,6,7,8-tetrahydroindeno...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceuticals (Basel)
Hauptverfasser: El-Awaad, Ehab, Birus, Robin, Marminon, Christelle, Bouaziz, Zouhair, Ballentin, Laurens, Aichele, Dagmar, Le Borgne, Marc, Jose, Joachim
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226678/
https://ncbi.nlm.nih.gov/pubmed/34198928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14060542
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