QSAR Model of Indeno[1,2-b]indole Derivatives and Identification of N-isopentyl-2-methyl-4,9-dioxo-4,9-Dihydronaphtho[2,3-b]furan-3-carboxamide as a Potent CK2 Inhibitor

Casein kinase II (CK2) is an intensively studied enzyme, involved in different diseases, cancer in particular. Different scaffolds were used to develop inhibitors of this enzyme. Here, we report on the synthesis and biological evaluation of twenty phenolic, ketonic, and para-quinonic indeno[1,2-b]in...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Molecules
Päätekijät: Haidar, Samer, Marminon, Christelle, Aichele, Dagmar, Nacereddine, Abdelhamid, Zeinyeh, Wael, Bouzina, Abdeslem, Berredjem, Malika, Ettouati, Laurent, Bouaziz, Zouhair, Le Borgne, Marc, Jose, Joachim
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982966/
https://ncbi.nlm.nih.gov/pubmed/31888043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25010097
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