Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity

OBJECTIVES: Preferential damage to fast, glycolytic myofibers is common in many muscle-wasting diseases, including Duchenne muscular dystrophy (DMD). Promoting an oxidative phenotype could protect muscles from damage and ameliorate the dystrophic pathology with therapeutic relevance, but developing...

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Detaylı Bibliyografya
Yayımlandı:Mol Metab
Asıl Yazarlar: Hardee, Justin P., Martins, Karen J.B., Miotto, Paula M., Ryall, James G., Gehrig, Stefan M., Reljic, Boris, Naim, Timur, Chung, Jin D., Trieu, Jen, Swiderski, Kristy, Philp, Ashleigh M., Philp, Andrew, Watt, Matthew J., Stroud, David A., Koopman, Rene, Steinberg, Gregory R., Lynch, Gordon S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2020
Konular:
Brief Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811171/
https://ncbi.nlm.nih.gov/pubmed/33359740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101157
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