Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice

Duchenne muscular dystrophy (DMD) is an X-linked genetic disease characterized by progressive muscle wasting and weakness and premature death. Glucocorticoids (e.g. prednisolone) remain the only drugs with a favorable impact on DMD patients, but not without side effects. We have demonstrated that gl...

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Vydáno v:Sci Rep
Hlavní autoři: Ham, Daniel J., Gardner, Anastasia, Kennedy, Tahnee L., Trieu, Jennifer, Naim, Timur, Chee, Annabel, Alves, Francesca M., Caldow, Marissa K., Lynch, Gordon S., Koopman, René
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736947/
https://ncbi.nlm.nih.gov/pubmed/31506484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49140-x
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