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Tranilast administration reduces fibrosis and improves fatigue resistance in muscles of mdx dystrophic mice
BACKGROUND: Duchenne muscular dystrophy (DMD) is a severe and progressive muscle-wasting disorder caused by mutations in the dystrophin gene that result in the absence of the membrane-stabilising protein dystrophin. Dystrophic muscle fibres are susceptible to injury and degeneration, and impaired mu...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3909382/ https://ncbi.nlm.nih.gov/pubmed/24476069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-7-1 |
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