Muscle-specific deletion of SOCS3 increases the early inflammatory response but does not affect regeneration after myotoxic injury

BACKGROUND: Muscles of old animals are injured more easily and regenerate poorly, attributed in part to increased levels of circulating pro-inflammatory cytokines. The Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling cascade is a key mediator of inflammatory cytok...

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Detalhes bibliográficos
Publicado no:Skelet Muscle
Main Authors: Swiderski, Kristy, Thakur, Savant S., Naim, Timur, Trieu, Jennifer, Chee, Annabel, Stapleton, David I., Koopman, René, Lynch, Gordon S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078888/
https://ncbi.nlm.nih.gov/pubmed/27800152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-016-0108-4
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