Making Fast-Twitch Dystrophic Muscles Bigger Protects Them from Contraction Injury and Attenuates the Dystrophic Pathology

The lack of functional dystrophin protein in Duchenne muscular dystrophy (DMD) renders muscle fibers highly fragile and susceptible to damage during contractions. Contraction-mediated injury is a major contributor to the progressive degeneration and etiology of muscle wasting in DMD. The prevailing...

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Hauptverfasser: Gehrig, Stefan M., Koopman, René, Naim, Timur, Tjoakarfa, Clarissa, Lynch, Gordon S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2010
Schlagworte:
Short Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797866/
https://ncbi.nlm.nih.gov/pubmed/19959813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090760
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