Notch and TNF-α signaling promote cytoplasmic accumulation of OLFM4 in intestinal epithelium cells and exhibit a cell protective role in the inflamed mucosa of IBD patients

Notch signaling is activated in the intestinal epithelial cells (IECs) of patients with inflammatory bowel disease (IBD), and contributes to mucosal regeneration. Our previous study indicated that TNF-α and Notch signaling may synergistically promote the expression of the intestinal stem cell (ISC)...

詳細記述

保存先:
書誌詳細
出版年:Biochem Biophys Rep
主要な著者: Kuno, Reiko, Ito, Go, Kawamoto, Ami, Hiraguri, Yui, Sugihara, Hady Yuki, Takeoka, Sayaka, Nagata, Sayaka, Takahashi, Junichi, Tsuchiya, Mao, Anzai, Sho, Mizutani, Tomohiro, Shimizu, Hiromichi, Yui, Shiro, Oshima, Shigeru, Tsuchiya, Kiichiro, Watanabe, Mamoru, Okamoto, Ryuichi
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2021
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808948/
https://ncbi.nlm.nih.gov/pubmed/33490652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100906
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