Notch and TNF-α signaling promote cytoplasmic accumulation of OLFM4 in intestinal epithelium cells and exhibit a cell protective role in the inflamed mucosa of IBD patients

Notch signaling is activated in the intestinal epithelial cells (IECs) of patients with inflammatory bowel disease (IBD), and contributes to mucosal regeneration. Our previous study indicated that TNF-α and Notch signaling may synergistically promote the expression of the intestinal stem cell (ISC)...

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Dades bibliogràfiques
Publicat a:Biochem Biophys Rep
Autors principals: Kuno, Reiko, Ito, Go, Kawamoto, Ami, Hiraguri, Yui, Sugihara, Hady Yuki, Takeoka, Sayaka, Nagata, Sayaka, Takahashi, Junichi, Tsuchiya, Mao, Anzai, Sho, Mizutani, Tomohiro, Shimizu, Hiromichi, Yui, Shiro, Oshima, Shigeru, Tsuchiya, Kiichiro, Watanabe, Mamoru, Okamoto, Ryuichi
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808948/
https://ncbi.nlm.nih.gov/pubmed/33490652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100906
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