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Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses
BACKGROUND: Polygenic risk scores (PRSs) can stratify populations into cardiovascular disease (CVD) risk groups. We aimed to quantify the potential advantage of adding information on PRSs to conventional risk factors in the primary prevention of CVD. METHODS AND FINDINGS: Using data from UK Biobank...
שמור ב:
| הוצא לאור ב: | PLoS Med |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7808664/ https://ncbi.nlm.nih.gov/pubmed/33444330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1003498 |
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