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Site-1 Protease-Derived Soluble (Pro)Renin Receptor Contributes to Angiotensin II–Induced Hypertension in Mice

Activation of PRR ([pro]renin receptor) contributes to enhancement of intrarenal RAS and renal medullary α-ENaC and thus elevated blood pressure during Ang II (angiotensin II) infusion. The goal of the present study was to test whether such action of PRR was mediated by sPRR (soluble PRR), generated...

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Publicat a:Hypertension
Autors principals: Feng, Ye, Peng, Kexin, Luo, Renfei, Wang, Fei, Yang, Tianxin
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803453/
https://ncbi.nlm.nih.gov/pubmed/33280408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.120.15100
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