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COX-2-independent activation of renal (pro)renin receptor contributes to DOCA-salt hypertension in rats

It has been shown that cyclooxygenase (COX)-2-dependent activation of renal (pro)renin receptor (PRR) contributes to angiotensin II (ANG II)-induced hypertension. However, less is known about the involvement of this mechanism in ANG II-independent hypertension. The goal of the present study was to t...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Wang, Fei, Sun, Ying, Luo, Renfei, Lu, Xiaohan, Yang, Baoxue, Yang, Tianxin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642891/
https://ncbi.nlm.nih.gov/pubmed/32799674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00112.2020
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