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Renal medullary (pro)renin receptor contributes to angiotensin II-induced hypertension in rats via activation of the local renin–angiotensin system

BACKGROUND: (Pro)renin receptor (PRR) is a new component of the renin–angiotensin system and regulates renin activity in vitro. Within the kidney, PRR is highly expressed in the renal medulla where its expression is induced by angiotensin II infusion. The objective of the present study was to test a...

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Bibliografische gegevens
Gepubliceerd in:BMC Med
Hoofdauteurs: Wang, Fei, Lu, Xiaohan, Liu, Mi, Feng, Yumei, Zhou, Shu-Feng, Yang, Tianxin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641338/
https://ncbi.nlm.nih.gov/pubmed/26554902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-015-0514-1
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