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Renal medullary (pro)renin receptor contributes to angiotensin II-induced hypertension in rats via activation of the local renin–angiotensin system

BACKGROUND: (Pro)renin receptor (PRR) is a new component of the renin–angiotensin system and regulates renin activity in vitro. Within the kidney, PRR is highly expressed in the renal medulla where its expression is induced by angiotensin II infusion. The objective of the present study was to test a...

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Библиографические подробности
Опубликовано в: :BMC Med
Главные авторы: Wang, Fei, Lu, Xiaohan, Liu, Mi, Feng, Yumei, Zhou, Shu-Feng, Yang, Tianxin
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641338/
https://ncbi.nlm.nih.gov/pubmed/26554902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-015-0514-1
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