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Renal medullary (pro)renin receptor contributes to angiotensin II-induced hypertension in rats via activation of the local renin–angiotensin system

BACKGROUND: (Pro)renin receptor (PRR) is a new component of the renin–angiotensin system and regulates renin activity in vitro. Within the kidney, PRR is highly expressed in the renal medulla where its expression is induced by angiotensin II infusion. The objective of the present study was to test a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:BMC Med
Hauptverfasser: Wang, Fei, Lu, Xiaohan, Liu, Mi, Feng, Yumei, Zhou, Shu-Feng, Yang, Tianxin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641338/
https://ncbi.nlm.nih.gov/pubmed/26554902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-015-0514-1
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