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Site-1 Protease-Derived Soluble (Pro)Renin Receptor Contributes to Angiotensin II–Induced Hypertension in Mice

Activation of PRR ([pro]renin receptor) contributes to enhancement of intrarenal RAS and renal medullary α-ENaC and thus elevated blood pressure during Ang II (angiotensin II) infusion. The goal of the present study was to test whether such action of PRR was mediated by sPRR (soluble PRR), generated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hypertension
Hauptverfasser: Feng, Ye, Peng, Kexin, Luo, Renfei, Wang, Fei, Yang, Tianxin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803453/
https://ncbi.nlm.nih.gov/pubmed/33280408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.120.15100
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