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(Pro)renin receptor decoy peptide PRO20 protects against adriamycin-induced nephropathy by targeting the intrarenal renin-angiotensin system

Adriamycin (ADR) administration in susceptible rodents such as the BALB/c mouse strain produces injury to the glomerulus mimicking human chronic kidney disease due to primary focal segmental glomerulosclerosis. The goal of the present study was to use this model to investigate antiproteinuric action...

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Pubblicato in:Am J Physiol Renal Physiol
Autori principali: Luo, Renfei, Yang, Kevin, Wang, Fei, Xu, Chuanming, Yang, Tianxin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701266/
https://ncbi.nlm.nih.gov/pubmed/32865014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00279.2020
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