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Intrarenal renin-angiotensin system mediates fatty acid-induced ER stress in the kidney

Obesity-related kidney disease is related to caloric excess promoting deleterious cellular responses. Accumulation of saturated free fatty acids in tubular cells produces lipotoxicity involving significant cellular dysfunction and injury. The objectives of this study were to elucidate the role of re...

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Publicado en:Am J Physiol Renal Physiol
Autores principales: Li, Chunling, Lin, Yu, Luo, Renfei, Chen, Shaoming, Wang, Feifei, Zheng, Peili, Levi, Moshe, Yang, Tianxin, Wang, Weidong
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971807/
https://ncbi.nlm.nih.gov/pubmed/26672616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00223.2015
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