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Intrarenal renin-angiotensin system mediates fatty acid-induced ER stress in the kidney

Obesity-related kidney disease is related to caloric excess promoting deleterious cellular responses. Accumulation of saturated free fatty acids in tubular cells produces lipotoxicity involving significant cellular dysfunction and injury. The objectives of this study were to elucidate the role of re...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Li, Chunling, Lin, Yu, Luo, Renfei, Chen, Shaoming, Wang, Feifei, Zheng, Peili, Levi, Moshe, Yang, Tianxin, Wang, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971807/
https://ncbi.nlm.nih.gov/pubmed/26672616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00223.2015
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