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Aliskiren restores renal AQP2 expression during unilateral ureteral obstruction by inhibiting the inflammasome
Ureteral obstruction is associated with reduced expression of renal aquaporins (AQPs), urinary concentrating defects, and an enhanced inflammatory response, in which the renin-angiotensin system (RAS) may play an important role. We evaluated whether RAS blockade by a direct renin inhibitor, aliskire...
Gardado en:
| Publicado en: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4971829/ https://ncbi.nlm.nih.gov/pubmed/25694485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00649.2014 |
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