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Intrarenal renin-angiotensin system mediates fatty acid-induced ER stress in the kidney
Obesity-related kidney disease is related to caloric excess promoting deleterious cellular responses. Accumulation of saturated free fatty acids in tubular cells produces lipotoxicity involving significant cellular dysfunction and injury. The objectives of this study were to elucidate the role of re...
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| Veröffentlicht in: | Am J Physiol Renal Physiol |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4971807/ https://ncbi.nlm.nih.gov/pubmed/26672616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00223.2015 |
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