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COX-2 mediates angiotensin II-induced (pro)renin receptor expression in the rat renal medulla

(Pro)renin receptor (PRR) is predominantly expressed in the distal nephron where it is activated by angiotensin II (ANG II), resulting in increased renin activity in the renal medulla thereby amplifying the de novo generation and action of local ANG II. The goal of the present study was to test the...

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Detalhes bibliográficos
Main Authors: Wang, Fei, Lu, Xiaohan, Peng, Kexin, Zhou, Li, Li, Chunling, Wang, Weidong, Yu, Xueqing, Kohan, Donald E., Zhu, Shu-Feng, Yang, Tianxin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080156/
https://ncbi.nlm.nih.gov/pubmed/24740788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00548.2013
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