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COX-2 mediates angiotensin II-induced (pro)renin receptor expression in the rat renal medulla

(Pro)renin receptor (PRR) is predominantly expressed in the distal nephron where it is activated by angiotensin II (ANG II), resulting in increased renin activity in the renal medulla thereby amplifying the de novo generation and action of local ANG II. The goal of the present study was to test the...

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Hlavní autoři: Wang, Fei, Lu, Xiaohan, Peng, Kexin, Zhou, Li, Li, Chunling, Wang, Weidong, Yu, Xueqing, Kohan, Donald E., Zhu, Shu-Feng, Yang, Tianxin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080156/
https://ncbi.nlm.nih.gov/pubmed/24740788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00548.2013
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