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More Than π–π–π Stacking: Contribution of Amide–π and CH–π Interactions to Crotonyllysine Binding by the AF9 YEATS Domain

Lysine crotonylation (Kcr) is a histone post-translational modification that is implicated in numerous epigenetic pathways and diseases. Recognition of Kcr by YEATS domains has been proposed to occur through intermolecular amide–π and alkene–π interactions, but little is known about the driving forc...

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Vydáno v:J Am Chem Soc
Hlavní autoři: Krone, Mackenzie W., Travis, Christopher R., Lee, Ga Young, Eckvahl, Hannah J., Houk, K. N., Waters, Marcey L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801323/
https://ncbi.nlm.nih.gov/pubmed/32926780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c06568
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