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Structure-guided development of YEATS domain inhibitors by targeting π-π-π stacking
Chemical probes of epigenetic ‘readers’ of histone posttranslational modifications (PTMs) have become powerful tools for mechanistic and functional studies of their target proteins in normal physiology and disease pathogenesis. Here we report the development of the first class of chemical probes of...
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| Pubblicato in: | Nat Chem Biol |
|---|---|
| Autori principali: | , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6503841/ https://ncbi.nlm.nih.gov/pubmed/30374167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0144-y |
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