Structure-guided development of YEATS domain inhibitors by targeting π-π-π stacking

Chemical probes of epigenetic ‘readers’ of histone posttranslational modifications (PTMs) have become powerful tools for mechanistic and functional studies of their target proteins in normal physiology and disease pathogenesis. Here we report the development of the first class of chemical probes of...

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Bibliografski detalji
Izdano u:Nat Chem Biol
Glavni autori: Li, Xin, Li, Xiao-Meng, Jiang, Yixiang, Liu, Zheng, Cui, Yiwen, Fung, Ka Yi, van der Beelen, Stan H. E., Tian, Gaofei, Wan, Liling, Shi, Xiaobing, Allis, C. David, Li, Haitao, Li, Yuanyuan, Li, Xiang David
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503841/
https://ncbi.nlm.nih.gov/pubmed/30374167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0144-y
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