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More Than π–π–π Stacking: Contribution of Amide–π and CH–π Interactions to Crotonyllysine Binding by the AF9 YEATS Domain

Lysine crotonylation (Kcr) is a histone post-translational modification that is implicated in numerous epigenetic pathways and diseases. Recognition of Kcr by YEATS domains has been proposed to occur through intermolecular amide–π and alkene–π interactions, but little is known about the driving forc...

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Dades bibliogràfiques
Publicat a:J Am Chem Soc
Autors principals: Krone, Mackenzie W., Travis, Christopher R., Lee, Ga Young, Eckvahl, Hannah J., Houk, K. N., Waters, Marcey L.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801323/
https://ncbi.nlm.nih.gov/pubmed/32926780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c06568
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