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More Than π–π–π Stacking: Contribution of Amide–π and CH–π Interactions to Crotonyllysine Binding by the AF9 YEATS Domain
Lysine crotonylation (Kcr) is a histone post-translational modification that is implicated in numerous epigenetic pathways and diseases. Recognition of Kcr by YEATS domains has been proposed to occur through intermolecular amide–π and alkene–π interactions, but little is known about the driving forc...
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| Publicado en: | J Am Chem Soc |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7801323/ https://ncbi.nlm.nih.gov/pubmed/32926780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c06568 |
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