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Combined immune checkpoint blockade increases CD8+CD28+PD-1+ effector T cells and provides a therapeutic strategy for patients with neuroblastoma

Immune checkpoint therapy has resulted in minimal clinical response in many pediatric cancers. We sought to understand the influence of immune checkpoint inhibition using anti-PD-1 and anti-CTLA-4 antibodies individually, in combination, and after chemotherapy on immune responses in minimal and esta...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Shirinbak, Soheila, Chan, Randall Y., Shahani, Shilpa, Muthugounder, Sakunthala, Kennedy, Rebekah, Hung, Long T., Fernandez, G. Esteban, Hadjidaniel, Michael D., Moghimi, Babak, Sheard, Michael A., Epstein, Alan L., Fabbri, Muller, Shimada, Hiroyuki, Asgharzadeh, Shahab
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801125/
https://ncbi.nlm.nih.gov/pubmed/33489468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1838140
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