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Exosome-Mediated Transfer of microRNAs Within the Tumor Microenvironment and Neuroblastoma Resistance to Chemotherapy

BACKGROUND: How exosomic microRNAs (miRNAs) contribute to the development of drug resistance in the context of the tumor microenvironment has not been previously described in neuroblastoma (NBL). METHODS: Coculture experiments were performed to assess exosomic transfer of miR-21 from NBL cells to hu...

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Bibliografske podrobnosti
izdano v:J Natl Cancer Inst
Main Authors: Challagundla, Kishore B., Wise, Petra M., Neviani, Paolo, Chava, Haritha, Murtadha, Mariam, Xu, Tong, Kennedy, Rebekah, Ivan, Cristina, Zhang, Xinna, Vannini, Ivan, Fanini, Francesca, Amadori, Dino, Calin, George A., Hadjidaniel, Michael, Shimada, Hiroyuki, Jong, Ambrose, Seeger, Robert C., Asgharzadeh, Shahab, Goldkorn, Amir, Fabbri, Muller
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651042/
https://ncbi.nlm.nih.gov/pubmed/25972604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv135
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