Exosome-Mediated Transfer of microRNAs Within the Tumor Microenvironment and Neuroblastoma Resistance to Chemotherapy

BACKGROUND: How exosomic microRNAs (miRNAs) contribute to the development of drug resistance in the context of the tumor microenvironment has not been previously described in neuroblastoma (NBL). METHODS: Coculture experiments were performed to assess exosomic transfer of miR-21 from NBL cells to hu...

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Vydáno v:J Natl Cancer Inst
Hlavní autoři: Challagundla, Kishore B., Wise, Petra M., Neviani, Paolo, Chava, Haritha, Murtadha, Mariam, Xu, Tong, Kennedy, Rebekah, Ivan, Cristina, Zhang, Xinna, Vannini, Ivan, Fanini, Francesca, Amadori, Dino, Calin, George A., Hadjidaniel, Michael, Shimada, Hiroyuki, Jong, Ambrose, Seeger, Robert C., Asgharzadeh, Shahab, Goldkorn, Amir, Fabbri, Muller
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651042/
https://ncbi.nlm.nih.gov/pubmed/25972604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv135
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