Tumor-associated macrophages promote neuroblastoma via STAT3 phosphorylation and up-regulation of c-MYC

Tumor-associated macrophages (TAMs) are strongly associated with poor survival in neuroblastomas that lack MYCN amplification. To study TAM action in neuroblastomas, we used a novel murine model of spontaneous neuroblastoma lacking MYCN amplification, and observed recruitment and polarization of TAM...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Hadjidaniel, Michael D., Muthugounder, Sakunthala, Hung, Long T., Sheard, Michael A., Shirinbak, Soheila, Chan, Randall Y., Nakata, Rie, Borriello, Lucia, Malvar, Jemily, Kennedy, Rebekah J., Iwakura, Hiroshi, Akamizu, Takashi, Sposto, Richard, Shimada, Hiroyuki, DeClerck, Yves A., Asgharzadeh, Shahab
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710942/
https://ncbi.nlm.nih.gov/pubmed/29207662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21066
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