Contribution of neuroblastoma-derived exosomes to the production of pro-tumorigenic signals by bone marrow mesenchymal stromal cells

The bone marrow (BM) niche is a microenvironment promoting survival, dormancy and therapeutic resistance in tumor cells. Central to this function are mesenchymal stromal cells (MSCs). Here, using neuroblastoma (NB) as a model, we demonstrate that NB cells release an extracellular vesicle (EVs) whose...

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Pubblicato in:J Extracell Vesicles
Autori principali: Nakata, Rie, Shimada, Hiroyuki, Fernandez, G. Esteban, Fanter, Rob, Fabbri, Muller, Malvar, Jemily, Zimmermann, Pascale, DeClerck, Yves A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505006/
https://ncbi.nlm.nih.gov/pubmed/28717423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2017.1332941
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