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Cancer-Associated Fibroblasts Share Characteristics and Pro-tumorigenic Activity with Mesenchymal Stromal Cells

Cancer-associated fibroblasts (CAF) have been suggested to originate from mesenchymal stromal cells (MSC), but their relationship to MSC is not clear. Here we have isolated from primary human neuroblastoma (NB) tumors a population of αFAP- and FSP-1-expressing CAF that share phenotypic and functiona...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Borriello, Lucia, Nakata, Rie, Sheard, Michael A., Fernandez, G. Esteban, Sposto, Richard, Malvar, Jemily, Blavier, Laurence, Shimada, Hiroyuki, Asgharzadeh, Shahab, Seeger, Robert C., DeClerck, Yves A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600847/
https://ncbi.nlm.nih.gov/pubmed/28687621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2586
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