Combined immune checkpoint blockade increases CD8+CD28+PD-1+ effector T cells and provides a therapeutic strategy for patients with neuroblastoma

Immune checkpoint therapy has resulted in minimal clinical response in many pediatric cancers. We sought to understand the influence of immune checkpoint inhibition using anti-PD-1 and anti-CTLA-4 antibodies individually, in combination, and after chemotherapy on immune responses in minimal and esta...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Shirinbak, Soheila, Chan, Randall Y., Shahani, Shilpa, Muthugounder, Sakunthala, Kennedy, Rebekah, Hung, Long T., Fernandez, G. Esteban, Hadjidaniel, Michael D., Moghimi, Babak, Sheard, Michael A., Epstein, Alan L., Fabbri, Muller, Shimada, Hiroyuki, Asgharzadeh, Shahab
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2021
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801125/
https://ncbi.nlm.nih.gov/pubmed/33489468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1838140
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