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Overexpression of p53 accelerates puberty in high-fat diet–fed mice through Lin28/let-7 system

High fat intake is one of the most important reasons of the surging prevalence of childhood obesity all over the world. Obesity and high fat intake have been revealed to cause premature activation of hypothalamo-pituitary-gonadal axis and central precocious puberty. The onset of puberty is controlle...

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Détails bibliographiques
Publié dans:Exp Biol Med (Maywood)
Auteurs principaux: Chen, Ting, Chen, Cailong, Wu, Haiying, Chen, Xiuli, Xie, Rongrong, Wang, Fengyun, Sun, Hui, Chen, Linqi
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797992/
https://ncbi.nlm.nih.gov/pubmed/32996351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370220961320
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