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Low Frequency of MKRN3 and DLK1 Variants in Chinese Children with Central Precocious Puberty

BACKGROUND: Central precocious puberty (CPP) is defined by gonadotropin-dependent development of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. MKRN3 and DLK1 are two genes, disease-causing variants of which have recently been discovered to cause idiopathic...

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Detalhes bibliográficos
Publicado no:Int J Endocrinol
Main Authors: Chen, Ting, Chen, Linqi, Wu, Haiying, Xie, Rongrong, Wang, Fengyun, Chen, Xiuli, Sun, Hui, Xiao, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794979/
https://ncbi.nlm.nih.gov/pubmed/31687022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9879367
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