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Overexpression of p53 accelerates puberty in high-fat diet–fed mice through Lin28/let-7 system

High fat intake is one of the most important reasons of the surging prevalence of childhood obesity all over the world. Obesity and high fat intake have been revealed to cause premature activation of hypothalamo-pituitary-gonadal axis and central precocious puberty. The onset of puberty is controlle...

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Dades bibliogràfiques
Publicat a:Exp Biol Med (Maywood)
Autors principals: Chen, Ting, Chen, Cailong, Wu, Haiying, Chen, Xiuli, Xie, Rongrong, Wang, Fengyun, Sun, Hui, Chen, Linqi
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797992/
https://ncbi.nlm.nih.gov/pubmed/32996351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370220961320
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