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The LIN28/let-7 Pathway in Cancer
Among all tumor suppressor microRNAs, reduced let-7 expression occurs most frequently in cancer and typically correlates with poor prognosis. Activation of either LIN28A or LIN28B, two highly related RNA binding proteins (RBPs) and proto-oncogenes, is responsible for the global post-transcriptional...
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| Udgivet i: | Front Genet |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5368188/ https://ncbi.nlm.nih.gov/pubmed/28400788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2017.00031 |
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