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Overexpression of p53 accelerates puberty in high-fat diet–fed mice through Lin28/let-7 system

High fat intake is one of the most important reasons of the surging prevalence of childhood obesity all over the world. Obesity and high fat intake have been revealed to cause premature activation of hypothalamo-pituitary-gonadal axis and central precocious puberty. The onset of puberty is controlle...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Chen, Ting, Chen, Cailong, Wu, Haiying, Chen, Xiuli, Xie, Rongrong, Wang, Fengyun, Sun, Hui, Chen, Linqi
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797992/
https://ncbi.nlm.nih.gov/pubmed/32996351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370220961320
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