Increased O-GlcNAcylation of Drp1 by amyloid-beta promotes mitochondrial fission and dysfunction in neuronal cells

As a dynamic organelle, mitochondria continuously fuse and divide with adjacent mitochondria. Imbalance in mitochondria dynamics leads to their dysfunction, which implicated in neurodegenerative diseases. However, how mitochondria alteration and glucose defect contribute to pathogenesis of Alzheimer...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Brain
Egile Nagusiak: Park, So Jung, Bae, Ji-Eun, Jo, Doo Sin, Kim, Joon Bum, Park, Na Yeon, Fang, Jianguo, Jung, Yong-Keun, Jo, Dong Gyu, Cho, Dong-Hyung
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2021
Gaiak:
Micro Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797154/
https://ncbi.nlm.nih.gov/pubmed/33422108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00727-w
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