Increased O-GlcNAcylation of Drp1 by amyloid-beta promotes mitochondrial fission and dysfunction in neuronal cells

As a dynamic organelle, mitochondria continuously fuse and divide with adjacent mitochondria. Imbalance in mitochondria dynamics leads to their dysfunction, which implicated in neurodegenerative diseases. However, how mitochondria alteration and glucose defect contribute to pathogenesis of Alzheimer...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Park, So Jung, Bae, Ji-Eun, Jo, Doo Sin, Kim, Joon Bum, Park, Na Yeon, Fang, Jianguo, Jung, Yong-Keun, Jo, Dong Gyu, Cho, Dong-Hyung
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Micro Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797154/
https://ncbi.nlm.nih.gov/pubmed/33422108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00727-w
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