Increased O-GlcNAcylation of Drp1 by amyloid-beta promotes mitochondrial fission and dysfunction in neuronal cells

As a dynamic organelle, mitochondria continuously fuse and divide with adjacent mitochondria. Imbalance in mitochondria dynamics leads to their dysfunction, which implicated in neurodegenerative diseases. However, how mitochondria alteration and glucose defect contribute to pathogenesis of Alzheimer...

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Detaylı Bibliyografya
Yayımlandı:Mol Brain
Asıl Yazarlar: Park, So Jung, Bae, Ji-Eun, Jo, Doo Sin, Kim, Joon Bum, Park, Na Yeon, Fang, Jianguo, Jung, Yong-Keun, Jo, Dong Gyu, Cho, Dong-Hyung
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2021
Konular:
Micro Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797154/
https://ncbi.nlm.nih.gov/pubmed/33422108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00727-w
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