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A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae

Proteostasis needs to be tightly controlled to meet the cellular demand for correctly de novo folded proteins and to avoid protein aggregation. While a coupling between translation rate and co-translational folding, likely involving an interplay between the ribosome and its associated chaperones, cl...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Rodríguez-Galán, Olga, García-Gómez, Juan J, Rosado, Iván V, Wei, Wu, Méndez-Godoy, Alfonso, Pillet, Benjamin, Alekseenko, Alisa, Steinmetz, Lars M, Pelechano, Vicent, Kressler, Dieter, de la Cruz, Jesús
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797049/
https://ncbi.nlm.nih.gov/pubmed/33330942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1200
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